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HIV/TB Immunology and Pathogenesis group

Head of the HIV Diversity and Pathogenesis group: Dr Wendy Burgers

The HIV/TB Immunology and Pathogenesis research group focuses on the immunology of HIV pathogenesis, seeking to understand how immune hyperactivation results in ineffective immunity, drives progression to disease, and what the mechanisms and mediators of aberrant activation are. We are also studying how HIV affects the immune response to Mycobacterium tuberculosis in HIV/TB co-infected individuals, at the level of both adaptive and innate immunity, in blood and at the site of disease, the lungs. The group consists of 2 postdocs, 3 PhD students, 2 MSc students and 1 research assistant. The work in the lab is funded by the Wellcome Trust, NIH and the European and Developing Countries Clinical Trials Partnership (EDCTP), with additional local funding from the MRC, NRF and NHLS Trust.

HIV/TB Immunology and Pathogenesis group